Thursday, 24 November 2016
Tuesday, 22 November 2016
Thursday, 3 November 2016
Breast-Conserving Therapy Versus Radical Mastectomy for Early Breast Cancer
The aim of this clinical study was to compare
breast-conserving therapy (BCT) and radical mastectomy (RM) in the treatment of
early breast cancer. Materials and methods: From March 1986 to the end of 1989,
117 women with a breast tumor of up to 2 cm in size were included in this
study; 66 women had a quadrantectomy, while 51 had a radical mastectomy.
Full axillary dissection was performed in all patients, while
adjuvant chemotherapy with cyclophosphamide, methotrexate and fluorouracil was
conducted in node-positive patients. Radiation to the remaining breast
parenchyma consisted of external-beam therapy, with or without regional
irradiation, without boost to the tumor bed. Results: The follow-up of patients
in the two treatment groups was limited to 240 months.
The mean period of observation (SD±) was 201.34 months (54.12
± 226.5) for the patients with breast-conserving therapy (BCT) and 195.84
months (35.1 ± 226.5) for the patients with radical mastectomy.
Monday, 24 October 2016
Multiple Myeloma, A Patient with Multiple Infections
We report a case of a 63-year-old male with recurrent severe
respiratory infections during the last year. During the last 6 months, he
presented with a gradual onset of generalized weakness, fatigue, myalgia and
anorexia. He self-medicated with intramuscular analgesics developing abscess of
the left gluteal area.
Throughout his hospitalization, anemia and kidney failure
were found without apparent cause. Wide antibiotic coverage was used
without signs of improvement. The patient was transferred to the University Hospital,
where under the criteria of recurrent infections, normocytic anemia, and kidney
failure; metastatic series imaging is sent.
The finding of lytic punched out lesions in the skull X ray
suggested multiple myeloma. Multiple Myeloma represents pathology of diverse
distribution. Although, the incidence is not reported in Honduras, we consider
it an underdiagnosed pathology often missed because it is not considered by
clinicians.
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